New test that may help improve development of treatments and detects the early stage of ageing which may prolong good health, researcher found.
Researcher’s new study found blood tests or ageing test that can provide an early warning of dementia, published in open-access journal Genome Biology. Study aimed to define set of genes associated with healthy ageing, 65 years olds. Profile found to be useful for determining early risk of such disease. This is also connected to better health for both women and men, though up to this very moment there are no drugs which could possibly stop dementia but new treatments can slow down disease if given ahead of time.
The study shows test can be distinguish between healthy person and patients with dementia. It can also be used to identify people in the early stages, patient with brain disease who have not yet developed symptoms can be detected, however, it gives no clues as to how to slow the ageing process. Researchers believed that through combining lifestyle factors and biological age, would give a more accurate picture of persons health. They are aware that through checking blood test could affect pensions to insurance premiums.
In statement of Dr Eric Karran of Alzheimer’s Research UK, ‘This study suggests a way to measure a person’s “biological age” and could reveal insights into the ageing process and why some people are more susceptible to age-related health conditions.’, ‘One of the biggest questions in human biology is how we age, and how this process impacts our wider health and risk for conditions like Alzheimer’s.
The RNA of healthy 65-year-old people been analysed by researchers, as well as the using information to develop a signature of 150 RNA genes that indicated “healthy ageing” and that patients diagnosed with Alzheimer’s disease had an altered “healthy ageing” RNA signature in their blood. By next year, the early version of said test could be ready for a clinical trial and technology could be used to identify those at risk for other age-related diseases.
Lead researcher James Timmons of King’s College London stated: “Our discovery provides the first robust molecular signature of biological age in humans and should be able to transform the way that age is used to make medical decisions.”, This includes identifying those more likely to be at risk of Alzheimer’s or dementia, as catching those at ‘early’ risk is key to evaluating potential treatments.
“This research could help in our quest to find new treatments by identifying people who are more likely to develop Alzheimer’s so that they can participate in clinical trials.” Dr Doug Brown, Alzheimer’s Society director of research added. IMAGE/ ALAMY